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Clinical Efficacy of the treatment of combination of Chinese and western medicine on Systemic Lupus Erythematosus:A Meta-analysis following the PRISMA

Volume 6, Issue 1, February 2021    |    PP. 7-23    |PDF (742 K)|    Pub. Date: December 27, 2020
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Author(s)
Yehao Luo, Master,Guangxi university of Traditional Chinese Medicine,Nanning, China; Master,College of Pharmacy, Minzu University of China, Beijing, China
Donghan Xu, Master,Macau University of Science and Technology,Macau, PR China
Luqiu Wei, Master,Guangxi university of Traditional Chinese Medicine,Nanning, China
Geer Chen, Master,Guangxi university of Traditional Chinese Medicine,Nanning, China; Master,Macau University of Science and Technology,Macau, PR China
Yuzhou Pang, Guangxi university of Traditional Chinese Medicine, PR China

Abstract
Systemic lupus erythematosus(SLE),known as lupus,is a chronic autoimmune disease and there is no cure for SLE.The western medication can improve syndromes to some extent,however,severe adverse drug reactions appear at the same time.Recently,it is confirmed that Chinese medicine also can have an excellent clinical efficacy on SLE.A meta-analysis was performed by using RevMan 5.3.A total of 9 randomized controlled trials, which involved 775 participants, met the inclusion criteria in this meta-analysis.It showed that the combination of Chinese and western medicine in the treatment of systemic lupus erythematosus(SLE) clearly improved the clinical efficacy compared with thecontrol group[OR=2.71,95%CI(1.75,4.19),P<0.00001],the levels of C3 increased[MD=0.11, 95%CI(0.04,0.17),P=0.002],the Hb levels increased [MD=7.02,95%CI(4.28,9.77),P<0.00001], the WBC levels increased [MD = 0.88, 95% CI (0.70,1.06),p<0.00001].In this study,the treatment of combination of Chinese and western medicine on SLE achieves more excellent clinical efficacy compared with the individual western medication therapy.

Keywords
Systemic Lupus Erythematosus, combination of Chinese and western medicine,meta-analysis, systemic review

Cite this paper
Yehao Luo, Donghan Xu, Luqiu Wei, Geer Chen, Yuzhou Pang, Clinical Efficacy of the treatment of combination of Chinese and western medicine on Systemic Lupus Erythematosus:A Meta-analysis following the PRISMA, SCIREA Journal of Clinical Medicine. Vol. 6 , No. 1 , 2021 , pp. 7 - 23 .

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