Familial Facial Palsy: Another Case Series of Seven Families from the Northern State, Sudan. Is it common?Familial Facial Palsy: Another Case Series of Seven Families from the Northern State, Sudan. Is it common?

Volume 9, Issue 1, February 2024     |     PP. 193-201      |     PDF (224 K)    |     Pub. Date: July 11, 2023
DOI: 10.54647/cm321119    54 Downloads     594 Views  

Author(s)

Mohamed Osman Abdelaziz, Faculty of Medicine & Health Sciences, University of Dongola

Abstract
Idiopathic facial (Bell's) palsy is a common neurologic disease. Familial facial palsy is an uncommon cause of idiopathic facial palsy affecting 4-14% of cases. Most cases follow an autosomal dominant inheritance pattern and many related genes were discovered. One previous study from the Northern State, Sudan reported six families with familial facial palsy. This study aims to describe familial facial palsy in seven families from the Northern State. The total number of cases of facial palsy in this study was 23 with 14 (60.9%) females from seven families compared to 34(38.2% female) cases from six families in the previous study. Two female patients developed recurrent episodes of facial palsy, whereas all other affected patients had a single episode. One of the two females with recurrent facial palsy had 10 episodes of facial palsy. Familial facial palsy may be common in the Northern Sate but further studies are needed to determine the prevalence and incidence in the state and other parts of Sudan. Genetic testing is recommended and family history is important.

Keywords
Bell's palsy, Familial facial palsy, Northern State, Sudan

Cite this paper
Mohamed Osman Abdelaziz, Familial Facial Palsy: Another Case Series of Seven Families from the Northern State, Sudan. Is it common?Familial Facial Palsy: Another Case Series of Seven Families from the Northern State, Sudan. Is it common? , SCIREA Journal of Clinical Medicine. Volume 9, Issue 1, February 2024 | PP. 193-201. 10.54647/cm321119

References

[ 1 ] Sajadi MM, Sajadi MR, Tabatabaie SM. The history of facial palsy and spasm: Hippocrates to Razi. Neurology. 2011 Jul 12;77(2):174-8. doi: 10.1212/WNL.0b013e3182242d23. PMID: 21747074; PMCID: PMC3140075
[ 2 ] Gronhoj Larsen, C., Gyldenlove, M., Jonch, A. E., et al. (2015). A three-generation family with idiopathic facial palsy suggesting an autosomal dominant inheritance with high penetrance. Case Reports in Otolaryngology, vol. 2015, article 683938
[ 3 ] Newadkar UR, Chaudhari L, Khalekar YK. Facial Palsy, a Disorder Belonging to Influential Neurological Dynasty: Review of Literature. N Am J Med Sci. 2016 Jul;8(7):263-7. doi: 10.4103/1947-2714.187130. PMID: 27583233; PMCID: PMC4982354
[ 4 ] National Institute of Neurological Disorders and Stroke. Bell's Palsy. Accessed on 6/6/2023 at: https://www.ninds.nih.gov/health-information/disorders/bells-palsy
[ 5 ] Qin D, Ouyang Z, Luo W (2009). Familial Recurrent Facial Palsy. Neurology India; 57(6):783. DOI: 10.4103/0028-3886.59478
[ 6 ] Orphanet. Rare Diseases. Accessed on 02/06/2023 at: file:///D:/FFP/FFP%20Lit%20Rev/Orphanet_%20Familial%20recurrent%20peripheral%20facial%20palsy.html
[ 7 ] Kubik M, Robles L, Kung D. Familial Bell's Palsy: A Case Report and Literature Review. Case Rep Neurol Med. 2012;2012:674981. doi: 10.1155/2012/674981. Epub 2012 Aug 5. PMID: 22934210; PMCID: PMC3420608
[ 8 ] Khair AM, Ibrahim K. Idiopathic Non-traumatic Facial Nerve Palsy (Bell's Palsy) in Neonates; An Atypical Age and Management Dilemma. Oman Med J. 2018 Jan;33(1):65-68. doi: 10.5001/omj.2018.12. PMID: 29468002; PMCID: PMC5798791.
[ 9 ] OMIM. Hereditary Congenital Facial Palsy. Accessed on 09/06/2023 at: https://www.omim.org/entry/601471
[ 10 ] Abdelaziz MO, Ziadan AA (2022). Familial Facial Palsy: A Case Series of Six Families from the Northern State, Sudan. Sudan Journal of Medical Sciences;17(1):128–137. DOI 10.18502/sjms.v17i1.10690
[ 11 ] Cancian, M., Giovannini, S., Angelini, A. et al. Melkersson–Rosenthal syndrome: a case report of a rare disease with overlapping features. Allergy Asthma Clin Immunol 15, 1 (2019). https://doi.org/10.1186/s13223-018-0316-z
[ 12 ] Qin D, Ouyang Z, Luo W. Familial recurrent Bell's palsy. Neurol India. 2009 Nov-Dec;57(6):783-4. DOI: 10.4103/0028-3886.59478
[ 13 ] Mohammad SA, Abdelaziz TT, Gadelhak MI, Afifi HH, Abdel-Salam GMH. Magnetic resonance imaging of developmental facial paresis: a spectrum of complex anomalies. Neuroradiology. 2018 Oct;60(10):1053-1061. doi: 10.1007/s00234-018-2063-8. Epub 2018 Aug 3. PMID: 30074067.