A new contribution to the knowledge of Adolescent Idiopathic Scoliosis (AIS)

Volume 9, Issue 1, February 2024     |     PP. 181-192      |     PDF (655 K)    |     Pub. Date: May 7, 2023
DOI: 10.54647/cm321076    79 Downloads     1099 Views  

Author(s)

Antonio Ferrante, centro Terapia Miofunzionale, Italy
Alberto Ferrante, Casa di cura Hermitage Capodimonte, Italy
Claudia Ferrante, Casa di cura Hermitage Capodimonte, Italy

Abstract
Introduction. The problem of idiopathic scoliosis is extremely complex and evaluated in different and discordant ways by the various specialists. All authors agree on one thing: the aethiology of adolescent idiopathic scoliosis still now, after many years of research and studies, is unknown! [1] Theories on AIS's aethiology have included mechanical, metabolic, hormonal, neuromuscular, growth, and genetic abnormalities. Amongst these, some factors may be epiphenomena rather than the cause itself. [1] Objective. Our research started from completely different bases, compared to specialized orthopedic studies, but perhaps, the possibility of looking for an explanation starting from a "clean slate", without any preconception, it allowed us to bring a partly new vision, based on our knowledge and skills, different from orthopedic ones. we wanted to show that many scoliosis find their origin in swallowing dysfunction. Methods. Our work was based on the use of devices suitable for measuring orofacial muscles (Myometer), muscle tone (surface electromyography), urinalysis to evaluate the catabolites of neuromediators and hormones produced. The results help to understand the mechanisms through which Scoliosis is created and worsened and indicate a way for its control and often its improvement. WORKING GROUP: N = 40 subjects aged 18-25 years not suffering from diseases of the spine, submitted to postural basic examination and electromyography at rest.
Rescreened with the same parameters after placement of the tongue at the level of the spot Palatine (emergence of the nasal-palatine nerve)
CONTROL GROUP: The same 40 patients constituted the control group, examined after the underlying condition, with different positioning of the tongue (contact with the lower incisors).
The control group has positioned the tongue in different position.
Results study 1 All the subjects, who present muscular imbalances and hypertones at the first examination, rebalanced the values ​​of the various muscles tested (oral, dorsal and paravertebral muscles) as soon as the tongue was placed in contact with the palatine receptors. The positioning of the tongue in different places did not give similar results. Discussion From the analysis of the tests, the tongue shows to have a noticeable effect on the overall posture. This effect is mediated by the change and the rebalancing of the muscular tone through a better functional relationship between the various muscular chains.
Results study 2 The analysis of the values of 5hydroxydolacetic acid, catabolite of serotonin in the urine of 24 hours, allowed to highlight a greater production of serotonin with the exercises of positioning the tongue in contact with the spot. Discussion Studies are confirmed that serotonin deficiency is implicated in the appearance of juvenile idiopathic scoliosis.

Keywords
Scoliosis, Melatonin, Serotonin, Pineal gland, Trigeminus nerve, Incorrect swallow

Cite this paper
Antonio Ferrante, Alberto Ferrante, Claudia Ferrante, A new contribution to the knowledge of Adolescent Idiopathic Scoliosis (AIS) , SCIREA Journal of Clinical Medicine. Volume 9, Issue 1, February 2024 | PP. 181-192. 10.54647/cm321076

References

[ 1 ] Cheung Kenneth M C , Wang T,  Qiu G X,  Luk Keith D K. Recent advances in the aetiology of adolescent idiopathic scoliosis Int Orthop 2008 Dec;32(6):729-34. doi: 10.1007/s00264-007-0393-y. Epub 2007 Jun 16.
[ 2 ] Girardo M, Bettini N, Dema E, Cervellati S. The role of melatonin in the pathogenesis of adolescent idiopathic scoliosis (AIS) Eur Spine J. 2011 May; 20(Suppl 1): 68–74.
[ 3 ] Bagnall KM, Raso VJ, Hill DL, Moreau M, Mahood JK, Jiang H, Russell G, Bering M, Buzzell GR. Melatonin levels in idiopathic scoliosis. Spine. 1997;21:1974–1978. doi: 10.1097/00007632-199609010-00006.
[ 4 ] Bagnall KM, Raso VJ, Hill DL, Moreau M, Mahood JK, Jiang H, Russell G, Bering M, Buzzell GR. Melatonin levels in idiopathic scoliosis. Diurnal and nocturnal serum melatonin levels in girls with adolescent idiopathic scoliosis. Spine. 1996;21:1974–1978. doi: 10.1097/00007632-199609010-00006.
[ 5 ] Fagan AB, Kennaway DJ, Sutherland AD. Total 24-hour melatonin secretion in adolescent idiopathic scoliosis: a case–control study. Spine. 1998;23(1):41–46. doi: 10.1097/00007632-199801010-00009. 
[ 6 ] Hilibrand AS, Blakemore LC, Loder RT, Greenfield ML, Farley FA, Hensinger RN, Hariharan M. The role of melatonin in the pathogenesis of adolescent idiopathic scoliosis. Spine. 1996;21:1140–1146. doi: 10.1097/00007632-199605150-00004.
[ 7 ] Machida M, Dubousset J, Imamura Y, Miyashita Y, Yamada T, Kimura J. Melatonin: a possible role in pathogenesis of adolescent idiopathic scoliosis. Spine.  1996;21:1147–1152. doi: 10.1097/00007632-199605150-00005
[ 8 ] Machida M, Murai H, Miyashita Y, Dubousset J, Yamada T, Kimura J. Pathogenesis of idiopathic scoliosis. Spine. 1999;24:1985–1989. doi: 10.1097/00007632-199910010-00004. 
[ 9 ] Machida M. Causes of idiopathic scoliosis. Spine. 1999;24:2576–2583. doi: 10.1097/00007632-199912150-00004
[ 10 ] Machida M, Dubousset J, Imamura Y, Iwaya T, Yamada T, Kimura J. Role of melatonin deficiency in the development of scoliosis in pinealectomised chickens. J Bone Joint Surg (Br) 1995;77-B:134–138. 
[ 11 ] Machida M, Dubousset J, Imamura Y, Iwaya T, Yamada T, Kimura J. An experimental study in chickens for the pathogenesis of idiopathic scoliosis. Spine. 1993;18:1609–1615. doi: 10.1097/00007632-199309000-00007.
[ 12 ] Ferrante A, Reed-Knight E, Bello A, Comentale P. Variazioni posturali conseguenti a cambiamento della posizione linguale ed a trattamento miofunzionale; Ortognatodonzia italiana, vol. 11, 3 -2002
[ 13 ] Halata Z., Baumann K.I.: “Sensory nerve endings in the hard palate and papilla incisiva of the rhesus monkey”; Anatomy and Embriology, vol.199, iss.5, pp 427-437,1999
[ 14 ] Ferrante A, Terapia miofunzionale, dalla deglutizione atipica ai problemi posturali”, Futura Publ. Society, 1997
[ 15 ] Ferrante A. Frenulo linguale corto. Centro Terapia miofunzionale.10/2017
[ 16 ] Ferrante Alberto. Modificazioni posturali secondarie alla variazione di funzione di alcuni muscoli del capo e del collo. Seconda Università di Napoli. Anno acc. 2005/2006
[ 17 ] Locati F. Fedeli R. Correlazione tra deglutizione scorretta, secrezione di serotonina e scoliosi in età evolutiva. Università La Sapienza, Roma, anno acc. 2008/2009.
[ 18 ] Tamburro S., Severino A., Nastro S.,Valutazione dei valori urinari di serotonina in ragazzi scoliotici, prima e dopo tre mesi di rieducazione della deglutizione. Università Sapienza, Roma, anno acc. 2009/2010.
[ 19 ] Avikainen VJ, Rezasoltani A, Kauhanen HA.:”Asymmetry of paraspinal EMG-time characteristics in idiopathic scoliosis”. J Spinal Disord. 1999 Feb;12(1):61-7.
[ 20 ] Cheung J, Halbertsma JP, Veldhuizen AG, Sluiter WJ, Maurits NM, Cool JC,vanHorn JR.: “A preliminary study on electromyographic analysis of the paraspinal musculature in idiopathic scoliosis”. Eur Spine J. 2005 Mar;14(2):130-7. Epub 2004 Sep 11.
[ 21 ] Gaudreault N, Arsenault AB, Lariviere C, DeSerres SJ, Rivard CH.: “Assessment of the paraspinal muscles of subjects presenting an idiopathic scoliosis: an EMG pilot study”.BMC Musculoskelet. Disord. 2005 Mar 10;6:14.
[ 22 ] Grassme R, Arnold D, Anders Ch, van Dijk JP, Stegeman DF, Linss W, Bradl I, Schumann NP, Scholle HCh: “Improved evaluation of back muscle SEMG characteristics by modelling”. Pathophysiology. 2005 Dec;12(4):307-12. Epub 2005 Oct 25.