Volume 4, Number 1 (2019)
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Home > Journals > SCIREA Journal of Biology > Archive > Paper Information

Advanced malignant melanoma of small bowel with lung metastases revealed by small bowel obstruction: A case report and literatures reviewed

Volume 4, Issue 1, February 2019    |    PP. 16-23    |PDF (2147 K)|    Pub. Date: April 7, 2019
89 Downloads     398 Views  

Author(s)
Kewen Zheng, Department of Urology, the First Affiliated Hospital of Wenzhou Medical University, the First Clinical College of Wenzhou Medical University, Wenzhou City, Zhejiang Province, 325000, P.R. China
Xiao Wu, Department of General Surgery, the Traditional Chinese Medicine Hospital of Yongjia Country, Wenzhou City, Zhejiang Province, 325000, P.R. China
Wei Chen, Department of Urology, the First Affiliated Hospital of Wenzhou Medical University, the First Clinical College of Wenzhou Medical University, Wenzhou City, Zhejiang Province, 325000, P.R. China
Kesi Zheng, Department of Oncology, Wenzhou People's Hospital, the Third Clinical College of Wenzhou Medical University, Wenzhou City, Zhejiang Province, 325000, P.R. China

Abstract
Melanoma diagnosed by small bowel obstructions (SBOs) as the initial clinical symptom is a relatively rare condition. We present a rare case of SBO that occurred in an adult woman with unsuspected small bowel melanoma, diagnosed by imaging, laparotomy and pathological examination. A 49-year-old female was sent to the emergency department complaining about abdominal pain and total constipation. CT scan showed small bowel obstruction and an enhanced mass located in the proximal jejunum segment. Exploratory laparotomy was performed, and a mass protruding to the jejunum which caused stenosis of intestine was revealed. Intestinal resection and anastomosis was performed. Pathological examination demonstrated melanoma diagnosis.

Keywords
melanoma, small bowel, small bowel obstruction, diagnosis, metastasis

Cite this paper
Kewen Zheng, Xiao Wu, Wei Chen, Kesi Zheng, Advanced malignant melanoma of small bowel with lung metastases revealed by small bowel obstruction: A case report and literatures reviewed, SCIREA Journal of Biology. Vol. 4 , No. 1 , 2019 , pp. 16 - 23 .

References

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[ 4 ] Xia J, Wang Y, Li F, Wang J, Mu Y, Mei X, Li X, Zhu W, Jin X, and Kai Yu. Expression of microphthalmia transcription factor, S100 protein, and HMB-45 in malignant melanoma and pigmented nevi. Biomed Rep. 2016;5(3):327-331.
[ 5 ] Faut M, Bisschop K, Jalving M, Been LB, Noordzij W, Peters FT, van der Leest AH, van Leeuwen BL and Hospers GA. Diagnosis and Treatment of Intestinal Melanoma Metastases in the Era of Effective Systemic Treatment: Annals of Surgery, 2015.
[ 6 ] Leonardi GC, Falzone L, Salemi R, Zanghì A, Spandidos DA, Mccubrey JA, Candido S and Libra M. Cutaneous melanoma: From pathogenesis to therapy (Review). Int J Oncol. 2018;52(4):1071-1080.
[ 7 ] Lens M, Bataille V and Krivokapic Z. Melanoma of the small intestine: Lancet Oncol. 2009;10(5):516-521.

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