Vitamin D Serum Level in Elderly: Its Association with The Incidence and Degree of Sarcopenia

Volume 9, Issue 1, February 2024     |     PP. 232-240      |     PDF (181 K)    |     Pub. Date: June 26, 2022
DOI: 10.54647/cm32831    61 Downloads     989 Views  

Author(s)

Niza Amalya, Department of Internal Medicine, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia
Wasis Udaya, Department of Internal Medicine, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia
Agus Sudarso, Department of Internal Medicine, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia
Syakib Bakri, Department of Internal Medicine, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia
Haerani Rasyid, Department of Internal Medicine, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia
Hasyim Kasim, Department of Internal Medicine, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia
Muh. Ilyas, Department of Internal Medicine, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia
Arifin Seweng, Department of Biostatistic, Faculty of Public Health, Hasanuddin University, Makassar, Indonesia

Abstract
Today, In Indonesia has been increased the number of life expectancy from the population of elderly in every year. For some research found that after the age of 60 years, mass of muscle and muscle strength decreases by up to 3% per year. The prevalence of sarcopenia is increasing. One of the causes of sarcopenia is vitamin D deficiency. This research aims to determine serum vitamin D levels from elderly: the relationship with the incidence and degree of sarcopenia. This cross-sectional research has conducted at Pos Pembinaan Terpadu Makassar with 107 elderly contributed during May until June 2021. SPSS ver. 25 was used in analyzing the data. From 107 subjects, 74.8% of women were dominated by old age. The maximum age is 60-69 years as much as 71%. Serum vitamin D levels were highest in conditions of insufficiency (52.3%), followed by sufficiency (36.4%) and deficiency (11.2%). From 107 subjects, 29 people (27.1%) had degree of sarcopenia: 27 people (93.1%) possible sarcopenia and 2 people (6.9%) sarcopenia. The mean serum vitamin D level was lower in sarcopenia (24.50 ng/ml) than in possible sarcopenia (28.26 ng/ml) with (p=0.634). The results of the analysis test showed that there was no statistically significant relationship between serum vitamin D levels: the relationship with the incidence and degree of sarcopenia (p>0.05). There is no relationship between Serum vitamin D levels in the elderly and degree of sarcopenia.

Keywords
Sarkopenia, Vitamin D, elderly

Cite this paper
Niza Amalya, Wasis Udaya, Agus Sudarso, Syakib Bakri, Haerani Rasyid, Hasyim Kasim, Muh. Ilyas, Arifin Seweng, Vitamin D Serum Level in Elderly: Its Association with The Incidence and Degree of Sarcopenia , SCIREA Journal of Clinical Medicine. Volume 9, Issue 1, February 2024 | PP. 232-240. 10.54647/cm32831

References

[ 1 ] Badan pusat statistik. Statistik penduduk lanjut usia 2021[Internet]. Jakarta: Badan Pusat Statistik; 2021 [cited 2022 feb 23]. Availabe from: http://www.bps.go.id
[ 2 ] Setiati S, Dwimartutie N. Sarcopenia. In: Setiati S, Alwi I, editors. Buku Ajar Ilmu Penyakit Dalam. 4th ed. Jakarta: Interna Pusblisher; 2015. p. 3717–23.
[ 3 ] Jang HC. How to diagnose sarcopenia in korean older adults? Ann Geriatr Med Res. 2018;22(2):73–9.
[ 4 ] Chen L, Woo J, Assantachai P, Auyeung T, Chou M, Iijima K, et al. Asian Working Group for Sarcopenia : 2019 Consensus Update on Sarcopenia Diagnosis and Treatment. J Am Med Dir Assoc [Internet]. 2020; Available from: https://doi.org/10.1016/j.jamda.2019.12.012
[ 5 ] Putra IGAW, Aryana IGPS, Astika IN, Kuswardhani RT, Putrawan IB, Purnami KR. Prevalensi sarkopenia dan frailty di desa Pedawe, Mangupura, Serai dan Songan. Intisari Sains Medis. 2020;11(2):546.
[ 6 ] Aspell N, Laird E, Healy M, Lawlor B, O’sullivan M. Vitamin D deficiency is associated with impaired muscle strength and physical performance in community-dwelling older adults: Findings from the english longitudinal study of ageing. Clin Interv Aging. 2019;14:1751–61.
[ 7 ] Conzade R, Grill E, Bischoff-Ferrari HA, Ferrari U, Horsch A, Koenig W, et al. Vitamin D in Relation to Incident Sarcopenia and Changes in Muscle Parameters Among Older Adults: The KORA-Age Study. Calcif Tissue Int [Internet]. 2019;105(2):173–82. Available from: https://doi.org/10.1007/s00223-019-00558-5
[ 8 ] Bischoff-Ferrari H, Borchers M, Gudat F. Vitamin D Receptor Expression in Human Muscle Tissue Decreases with Age. J Bone Miner Res. 2004;19(2):265–9.
[ 9 ] Kim DH, Meza CA, Clarke H, Kim JS, Hickner RC. Vitamin D and Endothelial Function. Nutrients. 2020;12(2):1–17.
[ 10 ] Hirani V, Cumming RG, Naganathan V, Blyth F, Couteur DGL, Hsu B, et al. Longitudinal associations between Vitamin D metabolites and Sarcopenia in older Australian men: The concord health and aging in men project. Journals Gerontol - Ser A Biol Sci Med Sci. 2018;73(1):131–8.
[ 11 ] Indirayani HW, Widajanti N, Firdausi H. Hubungan Defisiensi Kalsidiol Serum dan Derajat Sarkopenia pada Komunitas Usia Lanjut di Surabaya. J Penyakit Dalam Indones. 2020;7(1):29.
[ 12 ] Okuno J, Tomura S, Yabushita N, Kim M ji, Okura T, Tanaka K, et al. Effects of serum 25-hydroxyvitamin D3 levels on physical fitness in community-dwelling frail women. Arch Gerontol Geriatr. 2010;50(2):121–6.
[ 13 ] Murphy RA, Ip EH, Zhang Q, Boudreau RM, Cawthon PM, Newman AB, et al. Transition to Sarcopenia and Determinants of Transitions in Older Adults : A Population-Based Study. J Gerontol A Biol Sci Med Sci. 2014;69(6):751–8.
[ 14 ] Tessier AJ, Chevalier S. An update on protein, leucine, omega-3 fatty acids, and vitamin d in the prevention and treatment of sarcopenia and functional decline. Nutrients. 2018;10(8):1–17.
[ 15 ] Schneider DA, Trence DL. Possible role of nutrition in prevention of sarcopenia and falls. Endocr Pract. 2019;25(11):1184–90.