When sickle cell trait meets high-altitude

Volume 6, Issue 5, October 2021     |     PP. 290-292      |     PDF (288 K)    |     Pub. Date: August 15, 2021
DOI: 10.54647/cm32559    66 Downloads     3311 Views  


Sun Yong Lee, San Joaquin General Hospital, Internal medicine
Amandeep S Gill, San Joaquin General Hospital, Hematology & Oncology

Approximately 300 milion people worldwide have sickle cell trait and it is considered as a benign carrier state with relative protection to malaria. Despite of occasional reports, sickle cell trait can be associated with significant life-threatening coditions under certain situations such as hypoxia, dehydration, and strenuous physical exercise. Splenic infarct is one of the clinical complication from increasing red blood cell sickling and polymerization under low oxygen tension at high altitudes. It is crucial to be aware of the possible clinical complications with sickle cell trait and management to prevent morbidity and mortality.

Sickle cell trait; splenic infarct; high altitude

Cite this paper
Sun Yong Lee, Amandeep S Gill, When sickle cell trait meets high-altitude , SCIREA Journal of Clinical Medicine. Volume 6, Issue 5, October 2021 | PP. 290-292. 10.54647/cm32559


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