Particularities of renal change in burn disease

Volume 9, Issue 1, February 2024     |     PP. 10-14      |     PDF (102 K)    |     Pub. Date: June 19, 2017
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Babur M. Shakirov, M.D., Samarkand State Medical Institute, Burn department of RSCUMA Inter - Regional Burn Center, Samarkand, Uzbekistan.
Komil R. Tagaev, M.D., Samarkand State Medical Institute, Burn department of RSCUMA Inter - Regional Burn Center, Samarkand, Uzbekistan.
Erkin A. Hakimov, M.D., Samarkand State Medical Institute, Burn department of RSCUMA Inter - Regional Burn Center, Samarkand, Uzbekistan.

Acute renal failure is one of the major complications of burns and it is accompanied by a high mortality rate. Most renal failures occur either immediately after the injury or at a later period when sepsis develops. Fifty four materials of autopsies of died patients being treated at Burn Department of Samarkand branch of RSCUMA during 2006-2014 years. We studied morphological changes of micro vessels, structural and functional diversion in renal cells in burn disease. This study of kidneys made us possible to verity morphological substrate and pathogenesis of renal insufficiency in burn disease. From the study we can distinguish typical features of morphological changes in kidneys in burn disease; damage to micro vessels and cellular elements.

Burns, autopsies, microscope study of kidneys

Cite this paper
Babur M. Shakirov, M.D., Komil R. Tagaev, M.D., Erkin A. Hakimov, M.D., Particularities of renal change in burn disease , SCIREA Journal of Clinical Medicine. Volume 9, Issue 1, February 2024 | PP. 10-14.


[ 1 ] Alexeev A.A. Burn sepsis; diagnostics, prophylaxis and treatment: Summary of dissert. of DMS –M, 1993.
[ 2 ] Steinvall I, Bak Z, Sjoberg F: Acute kidney injury is common, parallels organ dysfunction or failure, and carries appreciable mortality in patients with major burns: a prospective exploratory cohort study. Crit Care 2008, 12: R124. 10.1186/cc7032
[ 3 ] Krutikov M.G. Infection of patients with burns: etiology, pathogenesis, diagnostics, profhylaxes and treatment: Summary from diss of DMS M, 2005.
[ 4 ] Mehta RL, Kellum JA, Shah SV, Molitoris BA, Ronco C, Warnock DG, Levin A: Acute Kidney Injury Network (AKIN): report of an initiative to improve outcomes in acute kidney injury. Crit Care 2007, 11: R31. 10.1186/cc5713
[ 5 ] Kramer GC, Lund T, Beckum O: Pathophysiology of burn shock and burn edema. In Total Burn Care. 3rd edition. Edited by Herndon DN. Philadelphia: Saunders Elsevier; 2007:93-104.
[ 6 ] Hakimov E.A., Shakirov B.M., Umarov Sh. Kidneys condition in multiorgan inefficiency resulting from burn disease. J.ournal of Medical and Biological Science Research 2015, Vol. 1 (2), pp. 10-12.
[ 7 ] Spies M. Multiple organ failure after trauma. British Medical Journal (IBMJ) IAAN: 0959-8146, vol. 313, ISS: 7057 Date: Sap 7, 1996, p. 573 - 574.
[ 8 ] Padman P., Shabbir M., Madhav B. // Am. J. Physiol. Lung. – 2005. – Vol. 288. – P. L3–L15.
[ 9 ] Herndon D.N. Total burn care // 2nd edition, W.B. Saunders; 2001.
[ 10 ] Lopes JA, Jorge S, Neves FC, Caneira M, da Costa AG, Ferreira AC, Prata MM: An assessment of the RIFLE criteria for acute renal failure in severely burned patients [letter]. Nephrol Dial Transplant 2007, 22: 285.
[ 11 ] Coca SG, Bauling P, Schifftner T, Howard CS, Teitelbaum I, Parikh CR: Contribution of acute kidney injury toward morbidity and mortality in burns: a contemporary analysis. Am J Kidney Dis 2007, 49: 517-523.
[ 12 ] Hoste EA, Damen J, Vanholder RC, Lameire NH, Delanghe JR, Hauwe K, Colardyn FA: Assessment of renal function in recently admitted critically ill patients with normal serum creatinine. Nephrol Dial Transplant 2005, 20: 747-753.