A Case of Lung Involvement in Extranodal NK/T cell lymphoma

Volume 4, Issue 2, April 2020     |     PP. 31-36      |     PDF (923 K)    |     Pub. Date: July 9, 2020
DOI:    217 Downloads     3268 Views  

Author(s)

Wenjuan Li, Department of Pulmonary and Critical Care Medicine, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510630, China
Ling Zhang, Department of Hematology, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510630, China
Xiangqi Huang, Department of Pathology, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou Guangdong 510630, China
Yuqi Zhou, Department of Pulmonary and Critical Care Medicine, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510630, China

Abstract
Background: Lung involvement is rare in Peripheral T cell lymphoma and lack of sufficient clinical study. The authors describe a rare case of lung involvement in a 41-year-old male patient with Extranodal NK/T cell lymphoma.
Methods: Hematologic investigation and left upper lobectomy of the lung were performed.
Results: The patient died 2 months after diagnosis of the disease.
Conclusions: Lung biopsy is important to confirm a diagnosis of primary pulmonary lymphoma. Lung involvement in T cell lymphoma as a prognostic factor needs further studies.

Keywords
Extranodal NK/T cell lymphoma, Lung lobectomy, Lung involvement

Cite this paper
Wenjuan Li, Ling Zhang, Xiangqi Huang, Yuqi Zhou, A Case of Lung Involvement in Extranodal NK/T cell lymphoma , SCIREA Journal of Medicine. Volume 4, Issue 2, April 2020 | PP. 31-36.

References

[ 1 ] Jaffe ES, Chan JK, Su IJ, et al. Report of the Workshop on Nasal and Related Extranodal Angiocentric T/Natural Killer Cell Lymphomas. Definitions, differential diagnosis, and epidemiology. Am J Surg Pathol 1996; 20: 103-111. (PMID:8540601)
[ 2 ] Chihara D, Ito H, Matsuda T, et al. Differences in incidence and trends of haematological malignancies in Japan and the United States. Br J Haematol 2014; 164: 536-545. (PMID:24245986)
[ 3 ] Chien CC, Lee HS, Lin MH, Hsieh PP. Primary extranodal natural killer/T-cell lymphoma of bronchus and lung: A case report and review of literature. Thorac Cancer 2016; 7: 140-144. (PMID:26816549)
[ 4 ] Chien CC, Lee HS, Lin MH, Hsieh PP. Primary pulmonary peripheral T-cell lymphoma: A case report and review of the literature. Thorac Cancer 2014; 5: 104-107. (PMID:26816549)
[ 5 ] Arber DA, Weiss LM, Albújar PF, Chen YY, Jaffe ES. Nasal lymphomas in Peru. High incidence of T-cell immunophenotype and Epstein-Barr virus infection. Am J Surg Pathol 1993; 17: 392-399. (PMID:8388175)
[ 6 ] Elenitoba-Johnson KS, Zarate-Osorno A, Meneses A, et al. Cytotoxic granular protein expression, Epstein-Barr virus strain type, and latent membrane protein-1 oncogene deletions in nasal T-lymphocyte/natural killer cell lymphomas from Mexico. Mod Pathol 1998; 11: 754-761. (PMID:9720504)
[ 7 ] Asano Y, Ohshima K, Yoshizawa S, Shiraishi G, Kato K. Modified CHOP in an aged patient with non-Hodgkin's lymphoma and probable extensive pulmonary involvement. Int J Hematol 1991; 54: 327-329. (PMID:1777606)
[ 8 ] Sakashita A, Ashizawa K, Minami K, et al. Localized ground glass opacities with multiple pulmonary small cysts in adult T-cell leukemia or lymphoma: an "alloy wheel" appearance. J Thorac Imaging 2009; 24: 321-324. (PMID:19935228)
[ 9 ] Yang L, Feng W, Chen C, et al. Primary pulmonary T-cell lymphoma mimicking pneumonia: A case report and literature review. Exp Ther Med 2016; 12: 365-368. (PMID: 27347063)
[ 10 ] Fraser T, Nagarur A. Pulmonary involvement of peripheral T-cell lymphoma manifesting as crazy paving pattern. Proc (Bayl Univ Med Cent) 2015; 28: 59-61. (PMID:25552801)