Biomedical Applications of Zinc Oxide Nanomaterials in Cancer Treatment: A review

Volume 9, Issue 1, February 2024     |     PP. 67-89      |     PDF (812 K)    |     Pub. Date: December 23, 2016
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Satinder Pal Kaur Malhotra, Faculty of Science and Technology, ICFAI University, Rajawala Road, Selaqui Dehradun-248197, India
T. K. Mandal, Faculty of Science and Technology, ICFAI University, Rajawala Road, Selaqui Dehradun-248197, India

Zinc oxide (ZnO) is a bio-safe material that possesses photo-oxidizing and photocatalysis impacts on chemical and biological species. ZnO holds a unique optical, chemical sensing, semiconducting, electric conductivity and piezoelectric properties. One of the most important features of ZnO nanomaterials is low toxicity and biodegradability. ZnO nanoparticles (NPs) is a low-cost, low-toxic, and versatile material, have shown to have a promising future in biological applications. Specific properties and characteristics of ZnO NPs, such as their inherent toxicity against cancerous cells, at least for cells of lymphocytic origin, their ability to induce intracellular reactive oxygen species (ROS) generation leading to death via an apoptotic mechanism, and their physiochemical properties leading to cellular uptake and ease of functionalization make them an appealing candidate for biomedical applications. In this review, the current status of the use of ZnO nano-materials for biomedical applications, such as biomedical imaging, drug delivery, gene delivery and cancer therapy has been addressed.

Zinc oxide nanomaterial, cancer treatment, biomedical imaging, drug delivery, gene delivery, biomarker mapping

Cite this paper
Satinder Pal Kaur Malhotra, T. K. Mandal, Biomedical Applications of Zinc Oxide Nanomaterials in Cancer Treatment: A review , SCIREA Journal of Chemistry. Volume 9, Issue 1, February 2024 | PP. 67-89.


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